What does measurement uncertainty mean in the laboratory?

The measurement uncertainty describes the range in which the “true” value of a measured variable lies with a given probability.

It is a measure of the reliability of a measurement result.

Factors that influence the measurement uncertainty

  • analytical precision (repeatability)
  • Calibration and reference materials
  • Sample handling and device conditions
  • Method deviations

Why is it important?

  • It enables the objective evaluation of different measurement methods
  • It describes the significance of clinical reference ranges
  • It supports laboratories in complying with standards such as ISO 15189

EQA-Schemes help to realistically estimate measurement uncertainties by providing comparative data from many laboratories.

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